科技服务 > PCR芯片实验服务 > 致癌基因和肿瘤抑制基因拷贝数PCR芯片 Oncogenes & Tumor Suppressor Genes Copy Number PCR Array

致癌基因和肿瘤抑制基因拷贝数PCR芯片 Oncogenes & Tumor Suppressor Genes Copy Number PCR Array

致癌基因和肿瘤抑制基因拷贝数PCR芯片 Oncogenes & Tumor Suppressor Genes Copy Number PCR Array
运费 ¥0.00
(库存 9999 件)
地区:上海
简介:Oncogenes & Tumor Suppressor Genes Copy Number PCR Array
提供商:SAB
服务名称:Oncogenes & Tumor Suppressor Genes Copy Number PCR Array
Human Oncogenes & Tumor Suppressor Genes Copy Number PCR Array

The Human Oncogenes & Tumor Suppressor Genes 384HC qBiomarker Copy Number PCR Array profiles the copy number of 95 genes reported to undergo frequent genomic alterations in human tumor DNA. Copy number alterations (CNA) are changes in DNA copy number that occur frequently in cancer. Identifying and profiling recurring DNA copy number changes in cancer may reveal CNA that can serve as new biomarkers and novel therapeutic targets for different subgroups. The genes on the array encode transcription factors, growth factors and their receptors, and kinases and phosphatases that regulate processes such as the cell cycle, cellular senescence, apoptosis, metastasis, drug metabolism, drug resistance, and p53, PI3K-AKT, growth factor and WNT signaling. Genes were chosen from the most frequently amplified or deleted genes relevant to oncogenic pathways and cancer biology based on the primary literature and public databases. This array may serve as a useful tool to help classify cancer samples by genotype and help verify gastric cancer phenotypic biomarkers. The array analyzes each gene in each sample in quadruplicate and includes a stable multi-copy reference assay for accurate copy number determination via appropriate DNA input normalization. The simplicity of the product format and operating procedure allow routine and reliable copy number profiling in any research laboratory with access to a real-time PCR instrument.
The qBiomarker Copy Number PCR Arrays are intended for molecular biology applications. This product is not intended for the diagnosis, prevention, or treatment of a disease.
96-well Plate, 384-well (4 × 96) Plate, and 100-well Disc formats are available.




AKT / PI-3-Kinase Signaling: AKT1, AKT2, PIK3CA.
Apoptosis: BCL2L1.
Cell Cycle: APC, AURKA, CCND1, CCND2, CCND3, CCNE1, CDK4, CDK6, CDKN1B, CDKN2A, CDKN2B, CDKN2C, FBXW7, MDM2, SKP2.
Cytoskeleton Regulators: CDC42, GRB7, NF1, NF2, PAK1, PTK2, STK11, TRIO.
DNA Damage & Repair: BRCA2, TOP2A.
Drug Metabolism: ABCB1, ATP7B.
ECM & Cell Adhesion: CD44, CDH1, CTNNB1, TNC.
Epigenetic Factors: DNMT3B, EZH2.
G-Protein Signaling: CDC42, GNAS, HRAS, KRAS, NRAS, PAK1, RAF1, SHC1.
Growth Factors: FGF1, FGF3, IL6, NOTCH3, TGFB2, VEGFA.
Metabolism: FHIT, MTAP, PDK1.
Phosphatases: FHIT, PTEN, PTPN1.
Receptor Tyrosine Kinases: ALK, EGFR, ERBB2, ERBB3, FGFR1, FGFR2, FGR, IGF1R, IGF2R, KDR, KIT, MET, PDGFRA, PDGFRB.
Telomeres & Telomerase: TERC, TERT


姓名
电话号码
电子邮箱
公司名称
地址
留言*
 
验证码
提交
我是混淆代码

如果您的浏览器未跳转,请点击此处进行游戏并领取优惠

技术支持 AI智能站群 luis888.vip@gmail.com